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SINGLE-DOSE · Peer-reviewed

The role of single-dose HPV vaccination in expanding access

Sixteen country-specific HPVsim models quantify how much single-dose HPV vaccination schedules — endorsed by WHO in 2022 — have already expanded access across Gavi-supported countries facing vaccine supply constraints.

Key findings

  • Single-dose adoption reached an estimated 18.5 million additional girls across 16 Gavi-supported countries by the end of 2024.
  • Projected to prevent at least 297,000 future cervical cancers, using a conservative two-dose counterfactual.
  • Number needed to vaccinate per cancer case prevented: around 63, in line with previously published estimates.

Outputs

At a glance

Themes
Single-dose vaccination GAVI Supply constraints LMIC
Setting
16 Gavi-supported countries

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